| RD | DATE | OPPONENT | VENUE | HOME/AWAY | LOCAL TIME | HOST TV NETWORK |
| 1 | Friday, Mar 23 | Essendon | Etihad Stadium | Away | 7:50pm | Seven |
| 2 | Thursday, Mar 29 | Richmond | Adelaide Oval | Home | 7:20pm | Seven |
| 3 | Saturday, Apr 7 | St Kilda | Etihad Stadium | Away | 7:25pm | Seven |
| 4 | Friday, Apr 13 | Collingwood | Adelaide Oval | Home | 7:20pm | Seven |
| 5 | Friday, Apr 20 | Sydney Swans | SCG | Away | 7:50pm | Seven |
| 6 | Saturday, Apr 28 | Gold Coast SUNS | Adelaide Oval | Home | 7:10pm | Foxtel |
| 7 | Saturday, May 5 | Carlton | Adelaide Oval | Home | 7:10pm | Seven |
| 8 | Saturday, May 12 | Port Adelaide | Adelaide Oval | Away | 4:40pm | Foxtel |
| 9 | Friday, May 18 | Western Bulldogs | Adelaide Oval | Home | 7:20pm | Seven |
| 10 | Sunday, May 27 | Melbourne | TIO Traeger Park | Away | 2:50pm | Seven |
| 11 | Sunday, Jun 3 | GWS GIANTS | Adelaide Oval | Home | 4:10pm | Foxtel |
| 12 | Sunday, Jun 10 | Fremantle | Perth Stadium | Away | 2:40pm | Foxtel |
| 13 | Saturday, Jun 16 | Hawthorn | MCG | Away | 7:25pm | Seven |
| 14 | Bye | |||||
| 15 | Saturday, Jun 30 | West Coast Eagles | Adelaide Oval | Home | 4:05pm | Foxtel |
| 16 | Friday, Jul 6 | Richmond | MCG | Away | 7:50pm | Seven |
| 17 | Thursday, Jul 12 | Geelong Cats | Adelaide Oval | Home | 7:20pm | Seven |
| 18 | Saturday, Jul 21 | Brisbane Lions | The Gabba | Away | 7:25pm | Foxtel |
| 19 | Saturday, Jul 28 | Melbourne | Adelaide Oval | Home | 7:10pm | Seven |
| 20 | Saturday, Aug 4 | Port Adelaide | Adelaide Oval | Home | 4:05pm | Foxtel |
| 21 | Saturday, Aug 11 | GWS GIANTS | UNSW Canberra Oval | Away | 7:25pm | Seven |
| 22 | Sunday, Aug 19 | North Melbourne | Adelaide Oval | Home | 4:10pm | Foxtel |
| 23 | TBC | Carlton | Etihad Stadium | Away | TBC | TBC |
2018 Fixture: Round-by-Round
Adelaide's full 2018 Toyota AFL Premiership Season Fixture
